For over 40 years Charlotte Erlanson-Albertsson, Professor of Medical and Physiological Chemistry at Lund University, has been researching the relationship between diet and human health and wellbeing. During the past 20 years Charlotte and her team have specialised in the areas of appetite regulation and energy balance.

Appetite is not just a sensation. It is a biochemical and physiological regulation in the body that is mostly controlled by the brain and based primarily on input from the stomach and intestinal tract.

Charlotte became interested in the reasons why many of the foods we eat today are so easily linked to overconsumption, resulting in overweight and related complications – so she began studying the mechanisms behind this phenomenon.

Charlotte and her research team found signals that regulate how we eat protein, fat and carbohydrates. They determined that sugar, through the combination of fat and sugar, is the primary means of becoming overweight.

Our hunger signals are stronger than our satiety signals

We have strong hunger signals that motivate us to eat when we require energy. On the other hand, we have weaker satiety signals, and we know that satiety is a sign of wellbeing. Satiety signals activate our reward system, make us feel satisfied and let us use the energy we’ve received from eating. This is important for our health and wellbeing.

Thylakoids release satiety hormones

Thylakoids are a natural ingredient in green plants and are important for photosynthesis – the ability of plants to use sunlight as a source of energy. After years of research with the aim of increasing satiety signals without increasing energy intake, Charlotte found that thylakoids stimulate the release of satiety hormones when they are ingested along with food. In other words, thylakoids can also create energy and wellbeing in humans.

Appethyl® contains thylakoids

Several clinical studies at Lund University have demonstrated the beneficial health effects of Appethyl®: it promotes weight loss, reduces waist measurements and improves metabolic parameters like cholesterol and glucose levels in the blood. The effects and use of thylakoids are protected by three patents.


Through the years, Charlotte and her team have carried out many studies to ensure the effects of thylakoids on human health and wellbeing. This has resulted in the following patents.

Being overweight: thylakoids counteract excessive weight gain and obesity.

Snacking: thylakoids reduce cravings for sugar and snacking.

Prebiotic effect: thylakoids stimulate the presence of beneficial bacteria in gut flora.


In one study 35 women with a BMI between 25 and 33 limited themselves to three meals per day, while exercising 30 minutes per day over a 12-week period. Half of the group also received 5 g of thylakoids per day. Here are the results.
  • Thylakoid group – weight loss of 5 kg, were satiated and satisfied between meals.
  • Control group – weight loss of 3.5 kg, wanted to snack between meals.
The study was conducted at the Overweight and Diabetes Unit and at the Division of Occupational and Environmental Medicine, Skåne University Hospital (SUS), Lund, Sweden, and designed as a single-blind, single-centre, randomised and placebo-controlled, 12-week diet intervention study.